Neuroligins

Postsynaptic cell-adhesion molecules that bind presynaptic NEUREXINS to form calcium-dependent trans-synaptic adhesions. Neuroligins recruit synaptic scaffolding proteins (e.g., PSD-95) via their PDZ DOMAIN. The distribution and interaction with neurexins are regulated by ALTERNATIVE SPLICING. Alterations in genes encoding neuroligins or neurexins are associated with cognitive diseases such as AUTISM SPECTRUM DISORDER.

Also Known As:

Neuroligin

Carbohydrates: 22516
- Glycoconjugates: 1370
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - Cell Adhesion Molecules: 4912
        Neuronal Cell Adhesion Molecules: 9
        Neural Cell Adhesion Molecules: 1100
        Neuroligins: 180
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - Cell Adhesion Molecules: 4912
        Neuronal Cell Adhesion Molecules: 9
        Neural Cell Adhesion Molecules: 1100
        Neuroligins: 180
  - Membrane Proteins: 10262
    - Membrane Glycoproteins: 2277
      - Cell Adhesion Molecules: 4912
        Neuronal Cell Adhesion Molecules: 9
        Neural Cell Adhesion Molecules: 1100
        Neuroligins: 180
  - Nerve Tissue Proteins: 3
    - Neuroligins: 180
Biological Factors: 2560
- Antigens: 145631
  - Surface Antigens: 5857
    - Cell Adhesion Molecules: 4912
      - Neuronal Cell Adhesion Molecules: 9
        Neural Cell Adhesion Molecules: 1100
        Neuroligins: 180

Margaret T Butko Selected Research

Margaret T Butko Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure